Most popular quantity.
Untitled Document
Zyprexa (Olanzapine) is an atypical antipsychotic, approved by the FDA for the treatment of: schizophrenia; depressive episodes associated with bipolar disorder, as part of the Symbyax formulation; acute manic episodes and maintenance treatment in bipolar disorder.
Zyprexa (Olanzapine) is structurally similar to clozapine, and is classified as a thienobenzodiazepine. Zyprexa (Olanzapine) has a higher affinity for 5-HT2 serotonin receptors than D2 dopamine receptors.
Like most atypical antipsychotics, compared to the older typical ones, Zyprexa (Olanzapine) has a lower affinity for histamine, cholinergic muscarinic and alpha adrenergic receptors.
The mode of action of Zyprexa (Olanzapine)'s antipsychotic activity is unknown. It may involve antagonism at serotonin receptors. Antagonism of dopamine receptors is associated with extrapyramidal effects such as tardive dyskinesia, and with therapeutic effects. Antagonizing H1 histamine receptors causes sedation and may cause weight gain, although antagonistic actions at 5-HT2C receptors have also been implicated in weight gain.
As with all neuroleptic drugs, Zyprexa (Olanzapine) can cause tardive dyskinesia and rare, but life-threatening, neuroleptic malignant syndrome.
Other recognised side effects may include:
- akathisia
- amblyopia
- dry mouth
- dizziness
- sedation
- insomnia
- orthostatic hypotension
- weight gain (90% of users experience weight gain)
- increased appetite
- runny nose
- low blood pressure
- impaired judgment, thinking, and motor skills
- impaired spatial orientation
- impaired responses to senses
- seizure
- trouble swallowing
- dental problems and discoloration of teeth
- missed periods
- problems with keeping body temperature regulated
- apathy, lack of emotion
What is the shelf life of the pills?
- The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
|